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Deputy Secretary of State John Negroponte and Assistant Secretary of State Richard Boucher met with Pakistan's new leaders Wednesday in Islamabad. Officials in the new government have indicated to the top senior U.S. envoys that the U.S. relationship with Pakistan will have to change.

The election of Mike Johnson to House speaker means two Louisianans hold two of the top spots in House leadership. That could mean issues important to the state could get more attention in Congress.

NPR's Don Gonyea talks to Alec MacGillis of ProPublica about top Senate Republican Mitch McConnell's leadership in the context of the Senate GOP's failure to repeal or replace the Affordable Care Act.

Michel Martin talks to Daniel Levy, head of the U.S./Middle East Project and onetime adviser in the government of former Israeli Prime Minister Ehud Barak, about the fighting between Hamas and Israel.

Bridget Lancaster and Jack Bishop advise using ripe fruit, extra-firm tofu and poking your hamburgers so they don't puff up like tennis balls.

Americans are not alone waiting for President Obama to announce his new strategy in Afghanistan. Afghans also are waiting to hear how the U.S. plans to tackle the crisis in their country, where violence and instability have worsened.

Secretary of State Antony Blinken is back in the Middle East, reassuring the region that the U.S. is seeking to de-escalate tensions and pushing for more aid to get into Gaza

The top Democrat on the Senate Judiciary Committee has released a transcript of the panel's interview with Glenn Simpson. He's the founder of the political research shop Fusion GPS, which commissioned the infamous, unverified dossier ostensibly documenting connections between the Trump camp and Russia. In the interview, Simpson stands by the document.

The race to fill the California Senate seat last held by the late Dianne Feinstein is coming down to a fight for second place ahead of Tuesday's election because of California's unique primary system.

Donald Trump's former personal attorney Michael Cohen is set to be cross-examined Tuesday in the criminal trial of the former president.