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The reverberations from Thursday's presidential debate continue, alongside consequential Supreme Court rulings.

On Wednesday, the U.S. Supreme Court upheld laws in roughly half the states that ban transgender medical care for minors. The vote was 6-to-3, along ideological lines.

Two rulings — in federal and state courts — make it increasingly likely that Kroger might abandon its $24.6 billion plan to buy Albertsons. The merger aimed to combine two of America's largest supermarket chains.

NPR asks Michelle Bercovici, an employment lawyer who mostly represents federal employees, about what the Trump administration's offer to almost all federal workers to resign by Feb. 6 means for them.

Artemis II, the first crewed mission to the Moon in more than 50 years, is set to launch as early as 6:24 p.m. Wednesday.

The UNAIDS annual report warns that Trump-era HIV funding cuts could lead to 6 million more infections and 4 million deaths by 2029 — as low-income countries struggle to fill the gap.

Janice Burgess, the Nickelodeon television executive who oversaw shows like Blue Clues, Little Bill, and The Backyardigans, has died at 72. She's remembered for inspiring kids' sense of adventure.

Colorado has been the talk of college football, but they were beat by the Oregon Ducks 42-6. NPR's Michel Martin talks to Washington Post columnist Kevin Blackistone, who appears regularly on ESPN.

With former President Trump's announcement that an indictment for his role in the Jan. 6 attack on the Capitol is coming, tension on the campaign trail shows the tightrope GOP candidates must walk.

The sheer volume of loss felt by the music world in 2020 is almost overwhelming. Here is NPR's tribute to dozens of the musicians — founders and innovators across genres — who died this year.